Yes, in TurboTax Self-Employed Online, the Home Office Deduction appears under Expenses for your business. If you used TurboTax last year, you should see the Home Office topic already, so click Edit/Add to begin. If this is a new business, click the box for "Add expenses for this work," then scroll down to "Home Office." Click Add to begin that section of the interview.
The look-and-feel has changed, but the entry process is essentially the same.
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