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I'm seeing the same behavior, but even after trying the solutions mentioned to fully uninstall/re-install TurboTax is still crashing for a normal user.  Admin seems to run, but I don't want folks running as admins!  Normal user had been running before just fine, then something changed.

Followed this process:  CommunitySupportTurboTaxGet startedInstall or update productsRemove and reinstall TurboTax for Mac 

Every time a normal user tries to run the program, a crash log is created in:

/Library/Logs/com.intuit.turbotax.2021.2022-03-19_19-27-05-7980000.log (or similar with the date part changing)

This is the tail end of the log showing the failure causing the crash:

2022-03-19 12:27:10.009 TurboTax 2021[12015:284026] ESD:Validating xml Signature...
2022-03-19 12:27:10.011 TurboTax 2021[12015:284026] ESD:Validating xml Signature...
2022-03-19 12:27:10.015 TurboTax 2021[12015:284026] ESD:Validating xml Signature...
2022-03-19 12:27:10.017 TurboTax 2021[12015:284026] ESD:Validating xml Signature...
2022-03-19 12:27:10.021 TurboTax 2021[12015:284026] EngineUpdate - 22 packages info recieved from ESD
2022-03-19 12:27:10.021 TurboTax 2021[12015:284026] EngineUpdate - TTMac product is already up-to-date to version [phone number removed]
ERROR: KSMachineContext.c (192): void ksmc_suspendEnvironment(): thread_suspend (00000a03): (ipc/send) invalid destination port
ERROR: KSMachineContext.c (223): void ksmc_resumeEnvironment(): thread_resume (00000a03): (ipc/send) invalid destination port
2022-03-19 12:27:10.173 TurboTax 2021[12015:284026] Terminate called after uncaught c++ exception:
0 TurboTax 2021 [phone number removed]8740cb PrintStackAndTerminateOnUncaughtCPPException + 59
1 KSCrash 0x000000010ff9be10 _ZL21CPPExceptionTerminatev + 86
2 libc++abi.dylib 0x00007fff20415307 _ZSt11__terminatePFvvE + 8
3 libc++abi.dylib 0x00007fff204152a9 _ZSt9terminatev + 41
4 libdispatch.dylib 0x00007fff202a881a _dispatch_client_callout + 28
5 libdispatch.dylib 0x00007fff202b4b4f _dispatch_main_queue_callback_4CF + 940
6 CoreFoundation 0x00007fff20586f1e __CFRUNLOOP_IS_SERVICING_THE_MAIN_DISPATCH_QUEUE__ + 9
7 CoreFoundation 0x00007fff20548f18 __CFRunLoopRun + 2769
8 CoreFoundation 0x00007fff20547d80 CFRunLoopRunSpecific + 567
9 Foundation 0x00007fff21203617 -[NSRunLoop(NSRunLoop) runMode:beforeDate:] + 212
10 Foundation 0x00007fff2128c945 -[NSRunLoop(NSRunLoop) runUntilDate:] + 103
11 TurboTax 2021 [phone number removed]29d9fb _ZL39RunTheProductUpdatesCheckerModalSessionP24MTPApplicationController + 395
12 TurboTax 2021 [phone number removed]29d697 -[MTPApplicationController checkProductUpdates:didFinishSelector:] + 535
13 TurboTax 2021 [phone number removed]280124 -[MTPApplicationController checkForApplicationAndFormUpdates:] + 708
14 TurboTax 2021 [phone number removed]285cfd -[MTPApplicationController applicationDidFinishLaunching:] + 941
15 CoreFoundation 0x00007fff2053f77f __CFNOTIFICATIONCENTER_IS_CALLING_OUT_TO_AN_OBSERVER__ + 12
16 CoreFoundation 0x00007fff205db185 ___CFXRegistrationPost_block_invoke + 49
17 CoreFoundation 0x00007fff205db0ff _CFXRegistrationPost + 496
18 CoreFoundation 0x00007fff20510a34 _CFXNotificationPost + 795
19 Foundation 0x00007fff211acbc8 -[NSNotificationCenter postNotificationName:object:userInfo:] + 59
20 AppKit 0x00007fff22c84040 -[NSApplication _postDidFinishNotification] + 305
21 AppKit 0x00007fff22c83d92 -[NSApplication _sendFinishLaunchingNotification] + 208
22 AppKit 0x00007fff22c80f31 -[NSApplication(NSAppleEventHandling) _handleAEOpenEvent:] + 541
23 AppKit 0x00007fff22c80b87 -[NSApplication(NSAppleEventHandling) _handleCoreEvent:withReplyEvent:] + 665
24 Foundation 0x00007fff211d8316 -[NSAppleEventManager dispatchRawAppleEvent:withRawReply:handlerRefCon:] + 308
25 Foundation 0x00007fff211d8186 _NSAppleEventManagerGenericHandler + 80
26 AE 0x00007fff2628a7f3 _AppleEventsCheckInAppWithBlock + 15720
27 AE 0x00007fff26289f0e _AppleEventsCheckInAppWithBlock + 13443
28 AE 0x00007fff26282c23 aeProcessAppleEvent + 448
29 HIToolbox 0x00007fff28a058a2 AEProcessAppleEvent + 54
30 AppKit 0x00007fff22c7b210 _DPSNextEvent + 2046
31 AppKit 0x00007fff22c79545 -[NSApplication(NSEvent) _nextEventMatchingEventMask:untilDate:inMode:dequeue:] + 1364
32 AppKit 0x00007fff22c6b869 -[NSApplication run] + 586
33 AppKit 0x00007fff22c3fa6c NSApplicationMain + 816
34 TurboTax 2021 [phone number removed]36a467 main + 39
35 libdyld.dylib 0x00007fff2046df3d start + 1

This is on Big Sur.

Ideas?