Underpayment tax penalty because of long term capital gains-

Had to sell my mother in laws house in July 2018 which was a Life Estate and my spouse was a remainderman.

My mother in law is still alive and has been in a Nursing Home for several years.

We incurred large long term capital gains on sale of house and this resulted in an underpayment of taxes.

I knew there would be tax consequences given that the mother in law is still alive. 

Turbo Tax applied a penalty dollar amount and my question is  - Is this type of transaction something that might be appropriate in asking/requesting for a waiver of penalties?