It is possible that Pennsylvania will tax you on income from there if the arrangement is temporary and specifically if it is associated with Covid, or you have the opportunity to work in Pennsylvania but choose to telecommute instead.
Since you live in South Carolina, you should file a resident tax return there. When you enter your W-2 form, enter the withholdings as they are stated on the form, with the PA abbreviation in box 15 so it will not be assigned to South Carolina.
Since you have Pennsylvania tax withheld from your pay, you need to file a non-resident tax return there. If you decide you should not be taxed on your Pennsylvania income, you should notify your employer of this so they will stop withholding taxes there.
If you end up being taxed on the same income in Pennsylvania and South Carolina, you can compete a credit for taxes paid to another state on your South Carolina return. You should complete your Pennsylvania return first to make that calculation easier and more reliable in TurboTax.
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