So was there a $20 contribution to your wife's HSA in 2021? If not, there is no problem with your return, because you don't enter information from the 5498-SA on to your return. All there is an inconsistency between your 5498-SA and your records. And your HSA custodian's real records should support you, because I am reading your post as "the HSA custodian accidentally indicated two years in a row that there was a $20 contribution, but the second contribution wasn't real."
You are responsible to report only those contributions that you, your employer, or any other eligible person on the planet actually made to your HSA. But if you can demonstrate that the HSA custodian made a mistake reporting the second contribution, then don't report it.
Just keep good documentation of everything and stick it in your tax files, in the (probably unlikely) event that anyone ever asks.
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