W4 Married Filing Jointly - 1 spouse is a W2 and another is self-employed (schedule C)

We file as married Filing Jointly. I earn the most between my wife and I, and I am the W2 employee. My wife has her own sole proprietor business where we file a Schedule C, and she pays quarterly estimated taxes each quarter.

 

I cannot figure out what the correct way to fill out the W4 is for Step 2: "Multiple Jobs or Spouse Works". My wife has not filled out a W4, only I have. 

 

This Step 2 is the most confusing (it also points you to the Estimator, which really doesn't answer this question when you try using it).