IRA Withdrawal and Tax Payment

Hello,

One of my relatives is a retired senior, living on her social security only.  Her income tax payment has always been closing to none.  Last year she withdrew her IRA and bought a very small one-bed condo.  She received 1099-R and TurboTax calculated her tax return for 2021 is $16,000 and her ES for each quarter of 2022 is $4000.  She cannot afford that payment.  What does she do?   What about $4000 ES?  She surely won’t have that income in 2022.  How to eliminate ES?  Many thanks for any help.