Joanna was not implying that these were withholdings like for an employer. Instead she is pointing that you can make estimated tax payment online (if you like) by going to the IRS link she shared.
There are many types of payments you can make here (see this IRS webpage for types of payments), so it is easily possible to make your 1040-ES estimated tax payments here.
To be clear, you can't make the actual payments for 1040-ES through TurboTax. If you have a large shortfall in tax in one year (common enough with a lot of investment sales) then TurboTax will print four 1040-ES forms (one for each quarter) that you can use for the following year - but you have to mail the form in or use the online service.
Make sense?
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