Your question is not clear enough. First, are you filing Married Filing Separately or Married Filing Jointly?
The other responses are assuming you are filing separately. In that case they are both correct.
In case you are filing jointly then both your itemized deductions and your spouse's itemized deductions are entered into schedule A. TurboTax will report the standard deduction if it's higher than your schedule A deductions. Business deductions on schedule C have nothing to do with itemized deductions on schedule A.
