@rakibuzzaman you say you came into the USA on F-1 in 2016. That would generally mean that for 2020 you would still be an exempt person and therefore Non-Resident Alien. What am I missing here?
For 2021, yes you would be a Resident Alien for tax purposes and therefore can (a) file married Fling Joint and (b) use TurboTax to prepare/file your return.
You can get the ITIN issued to your spouse by applying for it ( form W-7) to the IRS OR, including the application along with your joint return and the ITIN would be issued retroactively
