How are you trying to save? Using the File -> save or File plus option key -> save as?
The file should always have a name - untitled would indicate a new tax file with no data in it.
If you installed from a CD, be sure that the CD is NOT in the CD drive.
Be sure you are not trying to save to a location that your user does not permissions to write (the default Documents Folder in your user account should be used.
**Disclaimer: This post is for discussion purposes only and is NOT tax advice. The author takes no responsibility for the accuracy of any information in this post.**
