In terms of the Online products, TurboTax Deluxe, Premier, and Self-Employed all can do a Schedule C; HOWEVER, support of expenses for Schedule C is very limited in TurboTax Deluxe and Premier. Most self-employed taxpayers will want to use TurboTax Self-Employed in order to maximize the amount of business deductions that they can take. See https://turbotax.intuit.com/personal-taxes/online/free-edition.jsp#tax-forms
Who might want to use Deluxe or Premier? A taxpayer who had received a one-off 1099-MISC for work as a contractor who doesn't have any business expenses.
