Estimated taxes on big mid-year lump of cap gains?

Normally I get taxes withheld from my paycheck, which is most of my earnings, but this year I had a very large sum of capital gains mid-year.  Do I need to pay estimated taxes on that sum before I file next year?  If so, can I just calculate the amount I think I owe (either 15% or 20% of the total) and send in a check for that amount along with the 1040-ES stub?  Or do I need to complete the full 1040-ES worksheet and set up some sort of quarterly payment?

 

Thanks!