What I think you're asking is if you can file a physically separate tax return. If your business is a sole-proprietorship or single member LLC, then no, you can't do that. You'll report it on a SCH C as a part of your personal tax return.
If your business is a multi-member LLC, partnership, C-Corp, S-Corp or joint venture, then you *have* to file a physically separate tax return using TurboTax Business (different from Home & Business).
