This is usually a problem with how the TurboTax program is interacting with your computer. The fist recommendation is to clear the cache and cookies on your computer as follows:
https://ttlc.intuit.com/community/troubleshooting/help/how-to-clear-your-cache/00/26135
The next step would be to try another web browser when you are ready to transmit.
It would also be helpful to load the program on another computer if possible.
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