From the IRS: Use Schedule A (Form 1040) to figure your itemized deductions. In most cases, your federal income tax will be less if you take the larger of your itemized deductions or your standard deduction.
New tax laws, effective with the 2018 tax year, did away with personal exemptions and greatly increased the standard deduction. If you have mortgage interest, lots of medical bills, lots of donations, then you might want to use Schedule A. Most people don't have more in deductions than the standard deduction.
