Unfortunately, it really depends on your situation. For me, the two biggest changes are the elimination of the exemptions and the capping of State/Local/Property taxes on the itemized deductions. If you always had itemized deductions above $24k, then the elimination of the exemptions is huge. If your itemized and standard were close in the past - hovering around 12k, then the elimination of the exemptions wouldn't be that bad because your new standard deduction makes up for the loss in exemptions.
