You have to make a 4th Qtr estimated payment by Jan 15, 2018.
Yes, form 2210, using the annualized method will reduce or eliminate the penalty due to a large income increase in the 4th qtr. But if you don't make a payment by Jan 15, it will only reduce, not eliminate, the penalty.
When TurboTax sees that you are subject to a penalty, the interview will ask if you want to use the annualized method.
