The reason for this question is to determine whether you had a business, as with a business you could deduct expenses associated with earning the income and TurboTax will then lead you through those questions related to expenses.
So either way you answer the question will be fine. If you say "yes", you will be brought through more screens related to a business, for which you can answer in the negative. And if you say "no", you will just be asked if you have any more 1099's to enter.
