If you take the standard deduction, there won't be a Schedule A filed, so the IRS will not see the charitable deductions and other deductions.
Most self employment stuff would be on a different form like a schedule C, that wouldn't be different if you took the standard deduction.
I am not qualified to speculate on whether they look for a pattern of charitable giving from year to year, but as long as you don't try to deduct more than you are allowed to, it should be fine.
