If you mean you will be given a Form 1099-NEC for work performed in 2025, then yes, you should pay estimated taxes of at least 15% of your net self-employment income, to cover the self-employment tax you will be subject to. In addition, you will likely be subject to income taxes of 12% to 22% of your taxable income, so you should pay in estimated taxes for that as well.
The first quarter estimated tax is Due April 15, so you should make your payment by then.
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