No, the sale of business property is handled the same whether you used the actual expenses method or the standard mileage rate. You should use the method that provides the best tax outcome. You will have to enter actual expenses and your mileage to be able to compare each year.
If you sell or otherwise dispose of depreciated business property for a gain, depreciation recapture permits the IRS to take back or “recapture” some of the tax benefits you received over the years through depreciation deductions. You also have to recapture a Section 179 deduction if the percentage of business use drops to 50% or less for any year during the property's recovery period. Depreciation Recapture: Definition, Calculation, and Examples
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