The e-file database does not "reset" with an amendment, as DoninGA points out.
However, the IRS has created a new way to potentially allow for e-filing this year.
Your wife can apply for an Identity Protection PIN "IP PIN" and when this is entered in TurboTax, the return may electronically file. If it rejects after this step, you will need to print the return and mail this year.
Keep in mind that once she has received an IP PIN, she will be required to retrieve a new pin annually to be able to electronically file a federal tax return.
Get an identity protection PIN
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