The home office deduction is limited to the net profit on your Schedule C. If there is any mortgage interest or real estate taxes they can be used in full on Schedule A, if you can itemize your deductions. TurboTax will calculate this for you.
You cannot claim more than the tentative profit of your business in a tax year. For instance, if your tentative profit is $100, then you cannot deduct $200 as home office expense. So, your business income can have a deduction limit. The home office deduction that is unused will carryover to the following year until you can use it. It start with Schedule C, line 29, tentative profit. These forms will give you an overview.
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