Yes, go in through the Stocks, Bonds, Mutual Funds link and choose Other from the Dropdown list.
This will be reported as an Investment Loss, rather than a loss on the sale of Personal Property (which is not deductible).
You don't actually enter your 1099-S, just the proceeds from it, but save it and record of any other closing costs you incur.
Here's more info on Sale of Inherited Home.
@brookh
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