That depends.
If you meet the substantial presence test, you can file as a US Resident for tax purposes and use TurboTax, but if you don't have an ITIN (Individual Taxpayer Identification Number) you won't be able to E-file. Instead you will need to print and send the tax return with Form W-7.
Click here for information about Form W-7.
If you don't meet the substantial presence test, you would need to file 1040NR, (Non-Resident Tax Return) which is NOT included in the TurboTax software. If that is the case, you CAN use SPRINTAX, which is an authorized partner of TurboTax.
Click this link for TurboTax Tax Tips for Resident and Non-resident Aliens
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