Do I need to issue a 1099-MISC to my acting agents and also send it to the IRS if I want to use the commissions that I pay them as a deduction/expense in my schedule c?

I know where to add the amounts in TurboTax. There is a "commissions" box right under "advertising" in business expenses but when i click on "more info" about comissions it starts mentioning issuing a 1099-MISC to agents/managers. I guess that kind of makes sense since you ARE paying them but I want to make sure that that's indeed necessary if you're planning on putting an amount in that "commissions" box.