If you took a distribution from a tax favored retirement account before retirement age and received a 1099-R you will need to file in order to calculate, report and pay any early distribution penalty for that retirement income.
While your actual taxable income may be zero after your standard deduction, there is an "extra" tax of 10% that is applied to money taken out of a retirement account before you reach age 59 1/2.
Since you mentioned a 403(b) distribution, you need to file. If your retirement plan withheld taxes when they sent you the money, you like will not have a balance due. If there were no taxes withheld at all, you should be prepared to make a payment (or a payment plan) for the IRS.
I hope this information helps!
Clarissa
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