@BeanLou , since you did not elaborate , I am going to assume that (a) you both have SSN, ; (b) both have work permit; (c) you both have lived in the USA long enough to meet the substantial Presence Test.
In such a case , your working for a Candian entity and performing the work in the USA, would mean that for US purposes, your income is sourced to USA..
You file form 1040 , jointly with your spouse ( for max tax benefit, usually ). TurboTax supports the preparation and filing of such returns.
You will also be subject to US Social Security & medicare taxes ---- Canada and US have Totalization agreement and thus you will pay such taxes to only one taxing authority with a certificate from that authority showing that you are covered.
Note that because you will be working for a Candain entity, if you choose to pay Social Security & Medicare to the USA, you will have to pay the full 15.3% as a self-employed -- you file Schedule-C and Schedule-SE.
Does this make sense ? Is there more I can do for you ?
pk
