Get your taxes done using TurboTax

Even if I figure out the amount I need taken out, my pay isn’t exact every pay check as I work hourly and average about 12-21 hours every week. Also for the tuition assistance that gets added at the end of the year to my income. My employer adds about 20k and pays taxes on them. How do I make sure they pay the right amount if I ask for a flat withholding? If I write 0 on line 5 will that fix it? Or can I ask for a percentage to be taken out at all times?