For any capital gains (crypto included), the IRS still uses the "pay as you go" system. This means that they expect payment on realized gains on a quarterly basis. The gains are not REALIZED until you've sold the investment.
It is safest to go ahead and file and pay quarterly estimated income taxes if you can.
I'm linking you to a TurboTax FAQ that explains how to make estimated tax payments.
How do I make estimated tax payments?
*** I am NOT a tax expert. I am a seasoned TurboTax user, and volunteer to provide assistance to TT users. Nothing I post is to be considered TAX ADVICE; I bear no legal liability for responses.***
