@ktsweety
Your itemized deductions will consist of:
1)the medical expenses in excess of 7.5% of your adjusted gross income
2) state and local income or sales tax plus other taxes such as real estate and personal property taxes. because you will be filing separately, the limit for these taxes is $5000 (not the $10K that other filing statuses get)
3) mortgage interest subject to any mortgage debt limits. as MFS the maximum amount of debt allowed is also cut in half $375K/$500K but could be less
4) charitable contributions
5) certain other deductions - rare.
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hopefully, you have no child dependents because you lose out on child-related credits if MFS. However, if you do and lived apart from your spouse for the last 6 months of 2022 and the child lived with you can actually file as head of household. which is better than MFS
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