Using Windows 10: Same issue. You have to open TurboTax as Administrator if the program just refuses to save no matter what you do. Type in Administrator in your search bar next to the Windows icon (bottom left screen). Click on pop up Administration Tools. Find your previously saved tax file if you can. Right click on the file you want to open and click open as Administrator. You should be good to save after that. Just be sure to only hit Save when saving your session. I found the can't save error when I hit "Save As" to put it in the place I wanted it. Immediate error. I had to close the program and reopen from TurboTax loosing all my work. At one point I had to restart my computer, because I impulsively hit save as.
