@dbdd3 wrote:
Can I amend my W4 for State and Federal now to have an extra amount withheld for my last few paychecks in 2022 so I hopefully can avoid a penalty?
Yes (at least with respect to your federal income tax liability).
Even though additional tax is withheld at year end, the tax is deemed to be spread evenly throughout the tax year with an equal amount paid on each installment due date.
See https://www.thetaxadviser.com/issues/2018/mar/minimizing-estimated-tax-payments.html
