Can I start a TurboTax return if I change my filing from married filing jointly to separately today?

I'm considering converting my 2021 filing from married filing jointly to married filing separately for each of us because TurboTax says that will save us some money, but I'm not sure if I can start anew on TurboTax to complete it by October 31, 2022. I need to know if I can start my wife's return today (or at least before October 31, 2022).