Yes, you can as long as it is incurred to make money.

IRS allows business deductions for ordinary and necessary business expenses.

The standard mileage rate for 2016 is 54 cents a mile. 

EDITED to add three pictures to show where to enter the Vehicle expenses. 

Last picture is for a 1065 return, first three were for Home & Business.

You click on Federal Taxes, then sub-heading Deductions, then go down the screen to Auto Expenses.  I have highlighted the areas in yellow.