Deduction (Line 40 Form 1040) and Exemption (Line 42 Form 1040) reduces your Taxable Income (Line 43 Form 1040).
The less your Taxable Income, the fewer Taxes (Line 44 Form 1040) you pay.
Sometimes Taxable Income could be zero.
If your Total Taxes (Line 63 Form 1040) is zero, then Line 64 Form 1040 Federal Income ax Withheld will be the same amount, and it doesn't matter if you Itemise or use Standard deduction.
With minimum information, that's all I can think about.