The requirement for claiming the Exclusion of Gain on the sale of your primary home requires that you owned and lived in the home 2 out of the last 5 years. If you do not meet that test, you will have to pay taxes on the gain from the sale.
Since you rented the home for 10 years, you will need to re-capture the depreciation you took (or should have taken) during the rental period. That means, basically, the depreciation taken would be deducted from the basis of the home in calculating the gain/loss on the sale.
You mentioned renovations. If you made improvements to the home prior to sale, you can add those improvements to the basis of the home. Improvements would include things that added to the value of the home, such as adding a room, renovating a kitchen, replacing a heating/ac system, etc. Improvements would not include regular maintenance of the home, like painting, repairs, etc.
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