My wife works for a non profit part time. No income. Other than that she is a homemaker. Is there any deductions I can use for her? Thanks,

[Anita01]

If you mean she donates her time doing volunteer work for a nonprofit, you cannot deduct anything for her time.  If she spends money out of pocket for things like transportation, you could take a charitable contribution for that, if the nonprofit is a registered 501(c)(3).  The nonprofit would have to sign a receipt for the donation.