I still need to file for 2022 but don't have 2021 year's return. Can I still file without that return?

[Critter-3]

Do you mean can you file your 2022 return before you get the 2021 refund ?   If so  YES you can.

Do you mean can you file your 2022 return before you file the 2021 return?  If so  YES you can... if you do then  to efile the 2022 return you will use a zero for the 2021 AGI. 

[rjs]

Your tax return is the form you send to the government that shows your income and calculates your tax. The money the government sends back to you is your refund. Do you mean that you do not have a copy of your 2021 tax return, or did not yet file your 2021 tax return, or do you mean that you have not received your 2021 refund?

You can file your 2022 tax return, even if you do not have a copy of your 2021 tax return or did not yet file your 2021 tax return. But it's possible that your 2021 tax return would contain an item that would affect your 2022 tax return, such as a capital loss carryover. If you have any such items, you have to at least complete your 2021 tax return, or have a copy of it, in order to do your 2022 tax return, even if you have not actually filed the 2021 tax return.