you can set up a new return for your sister's return using the same program & account that you used for your tax return. I do 5 different returns myself. Just go to the pulldowns at the top of turbo tax...select "file" & then " new tax return". this will bring up a screen which gives you the choice to import a previous return or start from scratch. i assume that you will not be importing, so click on the blue "Start a New Return" button