How do I change my profile status to "Married, Filing Separately"?

[keyway1]

TurboTax hides the Married Filing Separately option because it thinks it can save your marriage. Go to Personal Info and change your filing status manually. TurboTax may ask if you’re sure. Tell it yes.
It’s not a relationship crisis — it’s just the IRS. The software will eventually accept your decision.

[SharonD007]

If you started a joint tax return and all your information has been transferred over, it’s easier to just start with a new return.  You will have to create a new account.

If you want to stay in your current return, follow the steps below:

1. Open TurboTax
2. Go to the Personal Profile screen
3. Under Your info, select your name and Revisit
4. When you get to the About your household screen, update your marital status.

Refer to the TurboTax article How do I switch from filing jointly to filing separately? for more information.