TurboTax can automatically calculate your estimated tax payments and print out payment vouchers for you to send into the IRS. You can also use TurboTax TaxCaster to get an estimate of your overall tax picture and if you should make an estimated tax payment. If you are not sure if you need to pay estimates you can use the IRS withholding estimator.https://www.irs.gov/individuals/tax-withholding-estimator