2022 I have both 1099 self employment income, W-2 income from my spouse, retirement income and investment income what turbo tax package should I use

[DoninGA]

You would need to use the TurboTax Self-Employed online edition for your tax return.  The online editions for tax year 2022 should be available in early December.

If you want to use the TurboTax CD/Download editions to be installed on a personal computer, any of the desktop editions can be used but the Home & Business edition would be recommended.  Go to this TurboTax website for the 2022 desktop editions - https://turbotax.intuit.com/personal-taxes/cd-download/

[VolvoGirl]

You can enter Self Employment Income into Online Deluxe or Premier but if you have any expenses you will have to upgrade to the Self Employed version. Or use any of the Desktop CD/Download programs.   All the Desktop program have the same forms. 

How to enter income from Self Employment
https://ttlc.intuit.com/community/self-employed/help/how-do-i-report-income-from-self-employment/00/...

Is this your first time with self employment income?  I can give your some general info and links for it.  You will file a schedule C in your personal return for it.  You just file a regular 1040 as before with the schedule c.