Is there a tool which will help me estimate my 2021 taxes? My wife has the same job, but I am now a travel nurse and work out of state with wages and stipends for housing

[M-MTax]

There's Taxcaster......https://turbotax.intuit.com/tax-tools/calculators/taxcaster......but it's for 2020 now. If you can wait until Nov the new Turbotax programs for 2021 should be available.

[fanfare]

You need TurboTax deluxe cd/download program.

start a new tax return but enter you expected amounts for 2021.
In normal times, this is close enough.

BUT,

You will need to adjust for changes in the tax laws for 2021.

Since the Congress is  in chaos, it is hard to predict what will be different in 2021.