We cannot see any of your information. We do not know what your tax bracket is, nor do you mention how much you are considering taking out of your retirement account so we do not know if it will change your tax bracket.
If you are under 59 1/2, you will be subject to a 10% early withdrawal penalty plus ordinary income tax in whatever tax bracket you are in. If you take money out in 2020 you will receive a 1099R in late January/early February which you will need to enter on your 2020 tax return.
Here is a link to the tax rates for 2020:
Possibly .... but we have a graduated tax system so not all of the extra income will be taxed at the higher rate ...
Your tax bracket depends on your taxable income and your filing status. The amount withdrawn from the 401k is added to your other taxable income which may or may not put you in a higher bracket. That does not mean all of your income is taxed at the percentage of your total taxable income.
For example if you have $50,000 of taxable income: the first $9,875 is taxed at 10%. Then $30,249 is taxed at 12%. Then $9,876 is taxed at 22%
Tax Brackets for tax year 2020 - Single
10% - 0 to 9,875
12% - 9,876 to 40,125
22% - 40,126 to 85,525
24% - 85,526 to 163,300
32% - 163,301 to 207,350
If you took the money from your 401K for specific coronavirus related reasons, you may not be required to pay the 10% early withdrawal penalty for persons under age 59 1/2. See this for the specific issues that might qualify you to avoid the 10% penalty: https://www.irs.gov/newsroom/coronavirus-related-relief-for-retirement-plans-and-iras-questions-and-...