If I have a large capital gain from a stock trade during the year, do I have to pay taxes immediatly?
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Yes you should send in an estimated payment so you don't owe too much on your tax return or get hit with a penalty.
Here are the 1040ES instructions and blank forms (where to mail is on page 4)
https://www.irs.gov/pub/irs-pdf/f1040es.pdf
Or you can pay on the IRS website. Be sure to pick 2021 1040ES payment
https://www.irs.gov/payments
if your estimated payments + withholding is at least 110% of your tax due last year, that's all you have to put in to avoid penalty.
It won't matter how large your gain was.
OF COURSE, then you will pay the whole tax on the big gain on April 15th.
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