No, home office expenses cannot be deducted for an employee receiving a W-2 even if the employer requires it.
That would be an employee business expense and those are no longer deductible on your Federal return due to the Tax Cuts and Jobs Act. However, you may still want to enter the expenses in case your state tax return has not complied with the Federal changes. This is true for both 2018 and 2019 returns, and all other tax years through 2025 as of now.
For state purposes only, the expenses would be included on Form 2106. Search for 'form 2106' at the top of your TurboTax screen to get started.
If you are self-employed, then home office expenses are still deductible as a business expense on Schedule C.
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