It depends.   If you are a cryptominer, reporting mining activities on Schedule C, it is possible that these services (which you would be using to determine the value of virtual currency you receive when you secure the blockchain), would be an "ordinary and necessary expense" that you report on Schedule C.  However, if you are only involved in virtual currency investment (in other words, holding cryptocurrency in your crypto-wallet with the hopes that it is increasing in value), then your expenses can only be claimed if they can be included as an adjustment to basis.  An example of adjustment to basis would be something like this:  You purchase a crypto-coin for $100.  You hold it for a while, and then use the coin to purchase a product, and at the time you do, your coin is worth $200.  However, you are charged a $5 fee for the conversion.  Your adjusted basis is $105:  $100 for the original investment plus the $5 fee.  If using the crypto trader services constitutes this type of adjustment, you can deduct it.  Otherwise, it is not a deductible expense anymore as per above.