If the income is in Box 7 of your 1099-MISC, in TT Home & Business (or TT Online Self-Employed) it can be entered under the Business tab, in the Business Income section under Business Income and Expenses.  Non-employee compensation (Box 7) is considered self-employment income, which is reported as business income.  TT will generate a business return (Schedule C), on which you can deduct your allowable business expenses.  To the IRS, if you have self-employment income, you're a self-employed "business."

If the income is not in Box 7, enter the 1099-MISC in the Other Common Income section of TT, on the line for 1099-MISC, and go through the follow-up questions.

You would not enter the same 1099-MISC into both places.

You'll find detailed information here: https://ttlc.intuit.com/questions/2893577-does-a-1099-misc-mean-i-m-self-employed